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A Smart Thermometer Can Track Flu Real Time, Can Predict The Spread


A "smart thermometer" connected to a mobile phone app can track flu activity in real time and help predict how the infection will spread, scientists, say.

"We found the smart thermometer data are highly correlated with information obtained from traditional public health surveillance systems and can be used to improve forecasting of influenza-like illness activity, possibly giving warnings of changes in disease activity weeks in advance," said Aaron Miller, a postdoctoral scholar at University of Iowa (UI) in the US.

The study’s approach

Miller and senior study author Philip Polgreen, MD, UI associate professor of internal medicine and epidemiology, analyzed de-identified data from the commercially available Kinsa Smart Ear Thermometers and app, which recorded users’ temperature measurement over a study period from Aug. 30, 2015 to Dec. 23, 2017.

There were more than 8 million temperature readings generated by almost 450,000 unique devices. The smart thermometers encrypt device identities to protect user privacy and also give users the option of providing anonymous information on age or sex. Readings were reported from all 50 states and were aggregated to provide region and age-group specific flu activity estimates.

Inder Singh and Erin Koehler at Kinsa, Inc., the company that makes and sells the smart thermometers, were also part of the study team. They conceived and designed the Kinsa products for purposes of tracking the spread of illness and provided full access to de-identified data for Miller and Polgreen to independently analyze. Neither Miller nor Polgreen have a financial relationship with Kinsa, Inc.

Real-time data improves flu forecasting

The UI team compared the data from the smart thermometers to influenza-like illness (ILI) activity data gathered by the Centers for Disease Control and Prevention (CDC) from health care providers across the country. They found that the de-identified smart thermometer data were highly correlated with ILI activity at national and regional levels and for different age groups.

Current forecasts rely on this CDC data, but even at its fastest, the information is almost two weeks behind real-time flu activity.

The UI study showed that adding thermometer data, which captures clinically relevant symptoms (temperature) likely even before a person goes to the doctor, to simple forecasting models improved predictions of flu activity. This approach accurately predicted influenza activity at least three weeks in advance.

“Our findings suggest that data from smart thermometers are a new source of information for accurately tracking influenza in advance of standard approaches,” Polgreen says. “More advanced information regarding influenza activity can help alert health care professionals that influenza is circulating, help coordinate response efforts, and help anticipate clinic and hospital staffing needs and increases in visits associated with high levels of influenza activity.”

A clearer picture of flu

Miller notes the smart thermometers also provide a way to estimate which age groups are being most affected during a flu season, using de-identified data.

“Because the device gives users the option of voluntarily reporting anonymized information on sex and age, we were able to estimate age-group specific incidence,” he says. “Our results also suggest that influenza-like-illness moves more frequently from children to adults rather than vice-versa.”

Monitoring the duration of fever from the smart thermometer readings also revealed fevers occurring during flu season were more likely to last three to six days and much less likely to last only one day. Fevers lasting seven or more days were not at all seasonal.

The data also identified instances where users had a fever that went away for a few days and then returned. The researchers believe this so-called “biphasic” fever pattern may reflect more serious illnesses. The second temperature spike can indicate a secondary bacterial infection like pneumonia that sets in after the flu and can lead to more severe health problems, especially in older individuals.

“Being able to track the duration of fevers and the return of fevers could help us learn more about an influenza season as it is emerging and possibly provide information about other infections, including new emerging infectious diseases,” Polgreen says.
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